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Alignments

 
BioloMICS:
 
  • Minimum sequence size (8) Minimum size of a sequence.
     
  • Minimum numerator (0) Minimum numerator (0).
     
  • Single insertion penalty (0.5) Penalty for a single insertion.
     
  • Double insertion penalty (0.7) Penalty for a double insertion.
     
  • Mutation penalty (1.0) Penalty for a mutation.
     
  • Precise Precise.
     
  • Field algorithm Algorithms listed for different field types.
     
  • Alignment algorithm Biolomics, Blast, Fasta or MultiAlign.
     
  • Alignment method Logical, BestCase or ExactMatch.
 
Blast:
 
  • Minimum similarity to keep results Minimum similarity to keep results.
     
  • Minimum overlap to keep results Minimum overlap to keep results.
     
  • Overlap rating reward Overlap rating reward.
     
  • Gap creation penalty Penalty when creating a gap.
     
  • Gap extension penalty Penalty when extending a gap.
     
  • Maximum alignments to display Maximum number of alignments to display.
 
  • Maximum allowed time per alignment Maximum allowed time per alignment.
 
  • Minimum sequences length Minimum length of a sequence.
     
  • Penalty mismatch Penalty for a mismatch.
     
  • Reward match Reward for a match.
     
  • Word size Length of the initial words. Default is 11, but can be decreased (to a minimum of 7) to increase the sensitivity. When increasing the word size, the search speed will be increased.
     
  • Sequence type Blastn, Blastp, Blastx, TBlastn, TBlastx, Fastan or Fastap.
     
  • Select sorting mode Rating, Similarity or Probability.
     
Multiple alignments:
 
  • Strategy
  • Automatic detection of the most appropriate algorithm
  • Very fast progressive method with a rough guide tree
  • Fast progressive method
  • Accurate iterative method suitable for less than 200 sequences of similar length
  • Most accurate iterative refinement method suitable for less than 200 sequences
  • Accurate method suitable for less than 200 sequences containing large unalignable regions
     
 
Click Save to save the changes made and to close the Options dialog.